# Sepsis-associated acute kidney injury: recent advances in enrichment strategies, sub-phenotyping and clinical trials

*PRI Rank #14 · Topics and Trends in Most Cited Dialysis and Renal Disease Management Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/dialysis-and-renal-disease-management/2026/rank-14*

| Field | Value |
| --- | --- |
| Rank | #14 |
| 18m citations | 44 |
| Journal | Critical Care |
| Year | 2024 |
| DOI | 10.1186/s13054-024-04877-4 |
| Corresponding authors | Matthieu Legrand |
| Institution | UCSF, United States |

**Ranking page:** [Topics and Trends in Most Cited Dialysis and Renal Disease Management Papers, Class of 2026](https://pri.pepkio.com/top-papers/dialysis-and-renal-disease-management/2026)

**Paper link:** [10.1186/s13054-024-04877-4](https://doi.org/10.1186/s13054-024-04877-4)

## Topics

sepsis-associated acute kidney injury · sub-phenotyping · Enrichment strategies · clinical trial design · patient-centered clinical trial endpoints · critically ill patients · AKI outcome trials · biomarker-based enrichment · trial endpoint selection · sepsis sub-phenotypes · AKI sub-phenotypes · predictive enrichment · prognostic enrichment · sepsis clinical trials

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Dialysis and Renal Disease Management Papers, Class of 2026. https://pri.pepkio.com/top-papers/dialysis-and-renal-disease-management/2026. Accessed 2026-07-14.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```