# Knockdown of integrin β1 inhibits proliferation and promotes apoptosis in bladder cancer cells

*PRI Rank #18 · Topics and Trends in Most Cited Cell Adhesion Molecules Research Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/cell-adhesion-molecules-research/2026/rank-18*

| Field | Value |
| --- | --- |
| Rank | #18 |
| 18m citations | 28 |
| Journal | BioFactors |
| Year | 2024 |
| DOI | 10.1002/biof.2150 |
| Corresponding authors | Beichen Ding, Yaxuan Wang, Ming-Hua Ren |
| Institution | First Affiliated Hospital of Harbin Medical University, China |

**Ranking page:** [Topics and Trends in Most Cited Cell Adhesion Molecules Research Papers, Class of 2026](https://pri.pepkio.com/top-papers/cell-adhesion-molecules-research/2026)

**Paper link:** [10.1002/biof.2150](https://doi.org/10.1002/biof.2150)

## Topics

Integrin β1 · Integrin β1 · bladder cancer · proliferation inhibition · apoptosis induction · 5637 cell line · RT112 cell line · Extracellular matrix · PI3K/AKT signaling pathway · Cell migration · Cell invasion · ITGB1 knockdown · prognostic risk factor · CES1 · NTNG1 · SETBP1 · AIFM3 · Prognostic risk model · immunological status · Therapeutic target

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Cell Adhesion Molecules Research Papers, Class of 2026. https://pri.pepkio.com/top-papers/cell-adhesion-molecules-research/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```