# Integrin <i>β</i>8 Facilitates Macrophage Infiltration and Polarization by Regulating CCL5 to Promote LUAD Progression

*PRI Rank #17 · Topics and Trends in Most Cited Cell Adhesion Molecules Research Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/cell-adhesion-molecules-research/2026/rank-17*

| Field | Value |
| --- | --- |
| Rank | #17 |
| 18m citations | 29 |
| Journal | Advanced Science |
| Year | 2024 |
| DOI | 10.1002/advs.202406865 |
| Corresponding authors | Yue Gao, Yanbin Zhao |
| Institution | Harbin Medical University Cancer Hospital, China |

**Ranking page:** [Topics and Trends in Most Cited Cell Adhesion Molecules Research Papers, Class of 2026](https://pri.pepkio.com/top-papers/cell-adhesion-molecules-research/2026)

**Paper link:** [10.1002/advs.202406865](https://doi.org/10.1002/advs.202406865)

## Topics

Integrin αvβ8 · Integrin αvβ8 · Lung adenocarcinoma · Lung adenocarcinoma · tumor microenvironment · macrophage infiltration · macrophage polarization · M2 macrophage · CD163+ macrophages · THP-1 cells · A549 cells · CCL5 · CCL5 · PI3K/AKT/IRF9 pathway · IL-8 · IL-8 · interleukin 10 · interleukin 10 · SPI1 · tumor cell-macrophage feedback mechanism

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Cell Adhesion Molecules Research Papers, Class of 2026. https://pri.pepkio.com/top-papers/cell-adhesion-molecules-research/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```