# Focal adhesions contain three specialized actin nanoscale layers

*PRI Rank #14 · Topics and Trends in Most Cited Cell Adhesion Molecules Research Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/cell-adhesion-molecules-research/2026/rank-14*

| Field | Value |
| --- | --- |
| Rank | #14 |
| 18m citations | 34 |
| Journal | Nature Communications |
| Year | 2024 |
| DOI | 10.1038/s41467-024-46868-7 |
| Corresponding authors | Pekka Lappalainen |
| Institution | University of Helsinki, Finland |

**Ranking page:** [Topics and Trends in Most Cited Cell Adhesion Molecules Research Papers, Class of 2026](https://pri.pepkio.com/top-papers/cell-adhesion-molecules-research/2026)

**Paper link:** [10.1038/s41467-024-46868-7](https://doi.org/10.1038/s41467-024-46868-7)

## Topics

Focal adhesions · iPALM microscopy · actin filament layers · tropomyosin isoforms · Tpm1.6 · Tpm3.2 · α-actinin cross-linked actin filaments · adhesion maturation · adhesion disassembly · ACF-7/MACF1 · KANK-family proteins · microtubule plus-ends · microtubule targeting · Cell migration · tail retraction · mechanosensing · Extracellular matrix · actin filament layers · Adhesion dynamics

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Cell Adhesion Molecules Research Papers, Class of 2026. https://pri.pepkio.com/top-papers/cell-adhesion-molecules-research/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```