# Global prevalence of claudin 18 isoform 2 in tumors of patients with locally advanced unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma

*PRI Rank #10 · Topics and Trends in Most Cited Cell Adhesion Molecules Research Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/cell-adhesion-molecules-research/2026/rank-10*

| Field | Value |
| --- | --- |
| Rank | #10 |
| 18m citations | 44 |
| Journal | Gastric Cancer |
| Year | 2024 |
| DOI | 10.1007/s10120-024-01518-1 |
| Corresponding authors | Manish A. Shah |
| Institution | National Cancer Center Hospital East, Japan |

**Ranking page:** [Topics and Trends in Most Cited Cell Adhesion Molecules Research Papers, Class of 2026](https://pri.pepkio.com/top-papers/cell-adhesion-molecules-research/2026)

**Paper link:** [10.1007/s10120-024-01518-1](https://doi.org/10.1007/s10120-024-01518-1)

## Topics

CLDN18.2 · CLDN18.2 · Gastric cancer · gastroesophageal junction adenocarcinoma · zolbetuximab · Immunohistochemistry · HER2 expression · diffuse-type tumors · SPOTLIGHT trial · GLOW trial · ILUSTRO trial · biomarker prevalence · membranous CLDN18 staining · archival versus baseline concordance · locally advanced unresectable · metastatic disease · primary versus metastatic site · biopsy versus resection

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Cell Adhesion Molecules Research Papers, Class of 2026. https://pri.pepkio.com/top-papers/cell-adhesion-molecules-research/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```