# Relocalizing transcriptional kinases to activate apoptosis

*PRI Rank #14 · Topics and Trends in Most Cited Cancer-related Molecular Pathways Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/cancer-related-molecular-pathways/2026/rank-14*

| Field | Value |
| --- | --- |
| Rank | #14 |
| 18m citations | 52 |
| Journal | Science |
| Year | 2024 |
| DOI | 10.1126/science.adl5361 |
| Corresponding authors | Roman C. Sarott, Sai Gourisankar, Basel A. Karim, Michael R. Green, Gerald R. Crabtree, Nathanael S. Gray |
| Institution | Stanford University, United States |

**Ranking page:** [Topics and Trends in Most Cited Cancer-related Molecular Pathways Papers, Class of 2026](https://pri.pepkio.com/top-papers/cancer-related-molecular-pathways/2026)

**Paper link:** [10.1126/science.adl5361](https://doi.org/10.1126/science.adl5361)

## Topics

chemically induced proximity · kinase inhibitors · transcriptional activation · BCL6 · cyclin-dependent kinase · CDK9 · bivalent molecules · RNA polymerase II phosphorylation · pro-apoptotic gene expression · diffuse large B-cell lymphoma · germinal center response · kinase relocalization · BCL6-target genes · gain-of-function · context-specific transcription

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Cancer-related Molecular Pathways Papers, Class of 2026. https://pri.pepkio.com/top-papers/cancer-related-molecular-pathways/2026. Accessed 2026-10-28.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```