# p53 at the crossroads of tumor immunity

*PRI Rank #12 · Topics and Trends in Most Cited Cancer-related Molecular Pathways Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/cancer-related-molecular-pathways/2026/rank-12*

| Field | Value |
| --- | --- |
| Rank | #12 |
| 18m citations | 53 |
| Journal | Nature Cancer |
| Year | 2024 |
| DOI | 10.1038/s43018-024-00796-z |
| Corresponding authors | Anil K. Rustgi, Carol Prives |
| Institution | Columbia University Irving Medical Center, United States |

**Ranking page:** [Topics and Trends in Most Cited Cancer-related Molecular Pathways Papers, Class of 2026](https://pri.pepkio.com/top-papers/cancer-related-molecular-pathways/2026)

**Paper link:** [10.1038/s43018-024-00796-z](https://doi.org/10.1038/s43018-024-00796-z)

## Topics

p53 tumor suppressor · tumor immunity · immune checkpoint · T cell response · tumor microenvironment · immunosurveillance · cancer immunotherapy · antigen presentation · immune evasion · cytokine signaling · tumor-infiltrating lymphocytes · MHC class I · interferon response · immunogenic cell death · PD-L1 regulation

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Cancer-related Molecular Pathways Papers, Class of 2026. https://pri.pepkio.com/top-papers/cancer-related-molecular-pathways/2026. Accessed 2026-10-28.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```