# Targeting and engineering long non-coding RNAs for cancer therapy

*PRI Rank #4 · Topics and Trends in Most Cited Cancer-related molecular mechanisms research Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/cancer-related-molecular-mechanisms-research/2026/rank-4*

| Field | Value |
| --- | --- |
| Rank | #4 |
| 18m citations | 105 |
| Journal | Nature Reviews Genetics |
| Year | 2024 |
| DOI | 10.1038/s41576-024-00693-2 |
| Corresponding authors | Rory Johnson |
| Institution | University College Dublin, Ireland |

**Ranking page:** [Topics and Trends in Most Cited Cancer-related molecular mechanisms research Papers, Class of 2026](https://pri.pepkio.com/top-papers/cancer-related-molecular-mechanisms-research/2026)

**Paper link:** [10.1038/s41576-024-00693-2](https://doi.org/10.1038/s41576-024-00693-2)

## Topics

Long non-coding RNA · Long non-coding RNA · Long non-coding RNA · Cancer therapy · Antisense oligonucleotides · RNA interference · CRISPR-Cas systems · Long non-coding RNA · RNA therapeutics · RNA therapeutics · Long non-coding RNA · Long non-coding RNA · Long non-coding RNA · RNA delivery systems

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Cancer-related molecular mechanisms research Papers, Class of 2026. https://pri.pepkio.com/top-papers/cancer-related-molecular-mechanisms-research/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```