# Mitophagy mediated by BNIP3 and NIX protects against ferroptosis by downregulating mitochondrial reactive oxygen species

*PRI Rank #17 · Topics and Trends in Most Cited Cancer-related molecular mechanisms research Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/cancer-related-molecular-mechanisms-research/2026/rank-17*

| Field | Value |
| --- | --- |
| Rank | #17 |
| 18m citations | 58 |
| Journal | Cell Death and Differentiation |
| Year | 2024 |
| DOI | 10.1038/s41418-024-01280-y |
| Corresponding authors | Shun‐ichi Yamashita, Tomotake Kanki |
| Institution | Niigata University, Japan |

**Ranking page:** [Topics and Trends in Most Cited Cancer-related molecular mechanisms research Papers, Class of 2026](https://pri.pepkio.com/top-papers/cancer-related-molecular-mechanisms-research/2026)

**Paper link:** [10.1038/s41418-024-01280-y](https://doi.org/10.1038/s41418-024-01280-y)

## Topics

Mitophagy · BNIP3 · NIX · Ferroptosis · Mitochondrial reactive oxygen species · Mitochondrial reactive oxygen species · BNIP3 · Mitophagy · Ferroptosis · mitochondrial quality control · Oxidative stress · Cell death

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Cancer-related molecular mechanisms research Papers, Class of 2026. https://pri.pepkio.com/top-papers/cancer-related-molecular-mechanisms-research/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```