# Cancer-associated fibroblast subtypes modulate the tumor-immune microenvironment and are associated with skin cancer malignancy

*PRI Rank #11 · Topics and Trends in Most Cited Cancer Cells and Metastasis Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/cancer-cells-and-metastasis/2026/rank-11*

| Field | Value |
| --- | --- |
| Rank | #11 |
| 18m citations | 82 |
| Journal | Nature Communications |
| Year | 2024 |
| DOI | 10.1038/s41467-024-53908-9 |
| Corresponding authors | Maria Kasper, Beate M. Lichtenberger |
| Institution | Medical University of Vienna, Austria |

**Ranking page:** [Topics and Trends in Most Cited Cancer Cells and Metastasis Papers, Class of 2026](https://pri.pepkio.com/top-papers/cancer-cells-and-metastasis/2026)

**Paper link:** [10.1038/s41467-024-53908-9](https://doi.org/10.1038/s41467-024-53908-9)

## Topics

Cancer-associated fibroblasts · CAF heterogeneity · basal cell carcinoma · Squamous cell carcinoma · melanoma · Single-cell RNA sequencing · Spatial transcriptomics · Myofibroblastic CAFs · Matrix CAFs · Immunomodulatory CAFs · extracellular matrix synthesis · Immune infiltration · tumor nest ensheathing · cytokine expression · chemokine expression · Immune infiltration · cancer cell secretomes · Tumor microenvironment · Therapy resistance

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Cancer Cells and Metastasis Papers, Class of 2026. https://pri.pepkio.com/top-papers/cancer-cells-and-metastasis/2026. Accessed 2026-10-29.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```