# Targeting Pseudomonas aeruginosa biofilm with an evolutionary trained bacteriophage cocktail exploiting phage resistance trade-offs

*PRI Rank #20 · Topics and Trends in Most Cited Bacteriophages and microbial interactions Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/bacteriophages-and-microbial-interactions/2026/rank-20*

| Field | Value |
| --- | --- |
| Rank | #20 |
| 18m citations | 61 |
| Journal | Nature Communications |
| Year | 2024 |
| DOI | 10.1038/s41467-024-52595-w |
| Corresponding authors | Andrej Trampuž |
| Institution | Universität Münster, Germany |

**Ranking page:** [Topics and Trends in Most Cited Bacteriophages and microbial interactions Papers, Class of 2026](https://pri.pepkio.com/top-papers/bacteriophages-and-microbial-interactions/2026)

**Paper link:** [10.1038/s41467-024-52595-w](https://doi.org/10.1038/s41467-024-52595-w)

## Topics

Pseudomonas aeruginosa · Biofilm · Phage cocktails · in vitro-directed evolution · phage resistance trade-offs · Multidrug resistance · Lytic phages · Host range · isothermal microcalorimetry · quantitative polymerase chain reaction · Biofilm · dual-phage-resistance · Phage therapy · biofilm evolution assay · antimicrobial efficacy

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Bacteriophages and microbial interactions Papers, Class of 2026. https://pri.pepkio.com/top-papers/bacteriophages-and-microbial-interactions/2026. Accessed 2026-07-17.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```