# Diverse anti-defence systems are encoded in the leading region of plasmids

*PRI Rank #18 · Topics and Trends in Most Cited Bacteriophages and microbial interactions Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/bacteriophages-and-microbial-interactions/2026/rank-18*

| Field | Value |
| --- | --- |
| Rank | #18 |
| 18m citations | 62 |
| Journal | Nature |
| Year | 2024 |
| DOI | 10.1038/s41586-024-07994-w |
| Corresponding authors | David Burstein |
| Institution | Tel-Aviv University, Israel |

**Ranking page:** [Topics and Trends in Most Cited Bacteriophages and microbial interactions Papers, Class of 2026](https://pri.pepkio.com/top-papers/bacteriophages-and-microbial-interactions/2026)

**Paper link:** [10.1038/s41586-024-07994-w](https://doi.org/10.1038/s41586-024-07994-w)

## Topics

plasmid leading region · Anti-defense systems · Anti-CRISPR proteins · anti-restriction proteins · anti-SOS proteins · horizontal gene transfer · conjugation · CRISPR-Cas · Restriction-modification systems · SOS-response genes · single-stranded DNA promoters · antimicrobial resistance dissemination · plasmid establishment · Anti-defense systems · conjugative delivery systems · Phage immune evasion · mobile genetic elements

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Bacteriophages and microbial interactions Papers, Class of 2026. https://pri.pepkio.com/top-papers/bacteriophages-and-microbial-interactions/2026. Accessed 2026-07-17.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```