# Personalized bacteriophage therapy outcomes for 100 consecutive cases: a multicentre, multinational, retrospective observational study

*PRI Rank #1 · Topics and Trends in Most Cited Bacteriophages and microbial interactions Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/bacteriophages-and-microbial-interactions/2026/rank-1*

| Field | Value |
| --- | --- |
| Rank | #1 |
| 18m citations | 262 |
| Journal | Nature Microbiology |
| Year | 2024 |
| DOI | 10.1038/s41564-024-01705-x |
| Corresponding authors | Jean‐Paul Pirnay |
| Institution | Queen Astrid Military Hospital, Belgium |

**Ranking page:** [Topics and Trends in Most Cited Bacteriophages and microbial interactions Papers, Class of 2026](https://pri.pepkio.com/top-papers/bacteriophages-and-microbial-interactions/2026)

**Paper link:** [10.1038/s41564-024-01705-x](https://doi.org/10.1038/s41564-024-01705-x)

## Topics

Phage therapy · difficult-to-treat infections · Phage-antibiotic synergy · in vivo bacteriophage resistance selection · antibiotic re-sensitization · Phage neutralization · lower respiratory tract infections · skin and soft tissue infections · bone infections · bacterial pathogen eradication · concomitant antibiotic use · Phage cocktails · pre-adapted bacteriophages · reduced virulence in phage-resistant isolates · clinical improvement assessment · adverse drug reactions · retrospective observational study · Belgian consortium · real-world bacteriophage therapy outcomes

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Bacteriophages and microbial interactions Papers, Class of 2026. https://pri.pepkio.com/top-papers/bacteriophages-and-microbial-interactions/2026. Accessed 2026-07-17.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```