# Autologous DNA mobilization and multiplication expedite natural products discovery from bacteria

*PRI Rank #18 · Topics and Trends in Most Cited Bacterial Genetics and Biotechnology Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/bacterial-genetics-and-biotechnology/2026/rank-18*

| Field | Value |
| --- | --- |
| Rank | #18 |
| 18m citations | 33 |
| Journal | Science |
| Year | 2024 |
| DOI | 10.1126/science.abq7333 |
| Corresponding authors | Feng Xie, Haowen Zhao, Rolf Müller, Chengzhang Fu |
| Institution | Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Germany |

**Ranking page:** [Topics and Trends in Most Cited Bacterial Genetics and Biotechnology Papers, Class of 2026](https://pri.pepkio.com/top-papers/bacterial-genetics-and-biotechnology/2026)

**Paper link:** [10.1126/science.abq7333](https://doi.org/10.1126/science.abq7333)

## Topics

ACTIMOT · CRISPR-Cas9 · autologous DNA mobilization · cryptic biosynthetic gene clusters · Streptomyces · natural products discovery · Antibiotic resistance dissemination · large DNA fragment relocation · replicative plasmids · molecular cloning limitations · biosynthetic pathway activation · chemical diversity from bacterial genomes

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Bacterial Genetics and Biotechnology Papers, Class of 2026. https://pri.pepkio.com/top-papers/bacterial-genetics-and-biotechnology/2026. Accessed 2026-10-28.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```