# Optimal timing of anticoagulation after acute ischaemic stroke with atrial fibrillation (OPTIMAS): a multicentre, blinded-endpoint, phase 4, randomised controlled trial

*PRI Rank #19 · Topics and Trends in Most Cited Atrial Fibrillation Management and Outcomes Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/atrial-fibrillation-management-and-outcomes/2026/rank-19*

| Field | Value |
| --- | --- |
| Rank | #19 |
| 18m citations | 60 |
| Journal | The Lancet |
| Year | 2024 |
| DOI | 10.1016/s0140-6736(24)02197-4 |
| Corresponding authors | David J. Werring |
| Institution | University College London, United Kingdom |

**Ranking page:** [Topics and Trends in Most Cited Atrial Fibrillation Management and Outcomes Papers, Class of 2026](https://pri.pepkio.com/top-papers/atrial-fibrillation-management-and-outcomes/2026)

**Paper link:** [10.1016/s0140-6736(24)02197-4](https://doi.org/10.1016/s0140-6736(24)02197-4)

## Topics

atrial fibrillation · Ischemic stroke · Direct oral anticoagulants · Direct oral anticoagulants · Anticoagulation timing · Anticoagulation timing · Anticoagulation timing · Ischemic stroke · Intracranial hemorrhage · Thromboembolic events · unclassifiable stroke · Stroke severity · Noninferiority trial · blinded-endpoint design · 90-day composite outcome · modified intention-to-treat analysis

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Atrial Fibrillation Management and Outcomes Papers, Class of 2026. https://pri.pepkio.com/top-papers/atrial-fibrillation-management-and-outcomes/2026. Accessed 2026-07-14.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```