# Combined exposure of emamectin benzoate and microplastics induces tight junction disorder, immune disorder and inflammation in carp midgut via lysosome/ROS/ferroptosis pathway

*PRI Rank #1 · Topics and Trends in Most Cited Aquaculture disease management and microbiota Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/aquaculture-disease-management-and-microbiota/2026/rank-1*

| Field | Value |
| --- | --- |
| Rank | #1 |
| 18m citations | 69 |
| Journal | Water Research |
| Year | 2024 |
| DOI | 10.1016/j.watres.2024.121660 |
| Corresponding authors | Tong Xu, Shiwen Xu |
| Institution | Northeast Agricultural University, China |

**Ranking page:** [Topics and Trends in Most Cited Aquaculture disease management and microbiota Papers, Class of 2026](https://pri.pepkio.com/top-papers/aquaculture-disease-management-and-microbiota/2026)

**Paper link:** [10.1016/j.watres.2024.121660](https://doi.org/10.1016/j.watres.2024.121660)

## Topics

emamectin benzoate · microplastics · combined exposure · carp midgut · tight junction disorder · Immune system disorders · inflammation · lysosome · Reactive oxygen species · ferroptosis pathway · Intestinal barrier dysfunction · oxidative stress · lysosomal membrane permeabilization · Gut immunity

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Aquaculture disease management and microbiota Papers, Class of 2026. https://pri.pepkio.com/top-papers/aquaculture-disease-management-and-microbiota/2026. Accessed 2026-07-24.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```