# Decreased eggshell strength caused by impairment of uterine calcium transport coincide with higher bone minerals and quality in aged laying hens

*PRI Rank #17 · Topics and Trends in Most Cited Animal Nutrition and Physiology Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/animal-nutrition-and-physiology/2026/rank-17*

| Field | Value |
| --- | --- |
| Rank | #17 |
| 18m citations | 23 |
| Journal | Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology |
| Year | 2024 |
| DOI | 10.1186/s40104-023-00986-2 |
| Corresponding authors | Jing Wang |
| Institution | Chinese Academy of Agricultural Sciences, China |

**Ranking page:** [Topics and Trends in Most Cited Animal Nutrition and Physiology Papers, Class of 2026](https://pri.pepkio.com/top-papers/animal-nutrition-and-physiology/2026)

**Paper link:** [10.1186/s40104-023-00986-2](https://doi.org/10.1186/s40104-023-00986-2)

## Topics

Eggshell strength · uterine calcium transport · bone mineral quality · aged laying hens · Hy-line Brown laying hens · eggshell ultrastructure · mammillary knobs · effective layer · cellular calcium overload · apoptosis · p62 protein · caspase-8 · Bcl/Bax ratio · TUNEL assay · runt-related transcription factor 2 · osteocalcin · bone remodeling · endocortical bone · femoral bone resorption · humeral bone formation

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Animal Nutrition and Physiology Papers, Class of 2026. https://pri.pepkio.com/top-papers/animal-nutrition-and-physiology/2026. Accessed 2026-07-14.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```