# Genome-wide variation study and inter-tissue communication analysis unveil regulatory mechanisms of egg-laying performance in chickens

*PRI Rank #12 · Topics and Trends in Most Cited Animal Nutrition and Physiology Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/animal-nutrition-and-physiology/2026/rank-12*

| Field | Value |
| --- | --- |
| Rank | #12 |
| 18m citations | 25 |
| Journal | Nature Communications |
| Year | 2024 |
| DOI | 10.1038/s41467-024-50809-9 |
| Corresponding authors | Hong Li, Yiqiang Zhao, Xiangtao Kang, Xiaojun Liu |
| Institution | Henan Agricultural University, China |

**Ranking page:** [Topics and Trends in Most Cited Animal Nutrition and Physiology Papers, Class of 2026](https://pri.pepkio.com/top-papers/animal-nutrition-and-physiology/2026)

**Paper link:** [10.1038/s41467-024-50809-9](https://doi.org/10.1038/s41467-024-50809-9)

## Topics

Laying performance · TFPI2 · CAMK2D · OSTN · GnRH secretion · FSHβ · LHβ · granulosa cell proliferation · sex steroid hormones · APOA4 · ANGPTL2 · hypothalamic-pituitary-ovarian axis · inter-tissue crosstalk · hepatokine · adipokine · Multi-omics analysis · genome-wide variation · hypothalamic neuron cells · pituitary cells · avian reproduction

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Animal Nutrition and Physiology Papers, Class of 2026. https://pri.pepkio.com/top-papers/animal-nutrition-and-physiology/2026. Accessed 2026-07-14.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```