# Genomics‐informed captive breeding can reduce inbreeding depression and the genetic load in zoo populations

*PRI Rank #9 · Topics and Trends in Most Cited Animal Genetics and Reproduction Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/animal-genetics-and-reproduction/2026/rank-9*

| Field | Value |
| --- | --- |
| Rank | #9 |
| 18m citations | 24 |
| Journal | Molecular Ecology Resources |
| Year | 2024 |
| DOI | 10.1111/1755-0998.13967 |
| Corresponding authors | Samuel A. Speak, Cock van Oosterhout |
| Institution | University of East Anglia, United Kingdom |

**Ranking page:** [Topics and Trends in Most Cited Animal Genetics and Reproduction Papers, Class of 2026](https://pri.pepkio.com/top-papers/animal-genetics-and-reproduction/2026)

**Paper link:** [10.1111/1755-0998.13967](https://doi.org/10.1111/1755-0998.13967)

## Topics

Nesoenas mayeri · Nesoenas mayeri · genetic load · inbreeding depression · zoo populations · captive breeding · mutation-impact scores · Gallus gallus · Gallus gallus · in silico crossings · realized load · genomics-informed conservation · mate pair optimization · effective population size · Genome-wide variation · harmful genetic variants · threatened species restoration

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Animal Genetics and Reproduction Papers, Class of 2026. https://pri.pepkio.com/top-papers/animal-genetics-and-reproduction/2026. Accessed 2026-07-22.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```