# Genome engineering with Cas9 and AAV repair templates generates frequent concatemeric insertions of viral vectors

*PRI Rank #5 · Topics and Trends in Most Cited Animal Genetics and Reproduction Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/animal-genetics-and-reproduction/2026/rank-5*

| Field | Value |
| --- | --- |
| Rank | #5 |
| 18m citations | 34 |
| Journal | Nature Biotechnology |
| Year | 2024 |
| DOI | 10.1038/s41587-024-02171-w |
| Corresponding authors | Fabian P. Suchy, Ravindra Majeti, Hiromitsu Nakauchi |
| Institution | Stanford University, United States |

**Ranking page:** [Topics and Trends in Most Cited Animal Genetics and Reproduction Papers, Class of 2026](https://pri.pepkio.com/top-papers/animal-genetics-and-reproduction/2026)

**Paper link:** [10.1038/s41587-024-02171-w](https://doi.org/10.1038/s41587-024-02171-w)

## Topics

Cas9 · AAV repair templates · Genome editing · Concatemeric insertions · viral vectors · adeno-associated virus · homology-directed repair · CRISPR-Cas9 · template integration · off-target integration · Concatemeric insertions · AAV genome integration · Genome editing · chromosomal insertion · repair template design

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Animal Genetics and Reproduction Papers, Class of 2026. https://pri.pepkio.com/top-papers/animal-genetics-and-reproduction/2026. Accessed 2026-07-22.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```