# Pretransplant Screening for Prevention of Hyperacute Graft Loss in Pig-to-primate Kidney Xenotransplantation

*PRI Rank #16 · Topics and Trends in Most Cited Animal Genetics and Reproduction Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/animal-genetics-and-reproduction/2026/rank-16*

| Field | Value |
| --- | --- |
| Rank | #16 |
| 18m citations | 17 |
| Journal | Transplantation |
| Year | 2024 |
| DOI | 10.1097/tp.0000000000004958 |
| Corresponding authors | Kazuhiko Yamada |
| Institution | The Johns Hopkins School of Medicine, United States |

**Ranking page:** [Topics and Trends in Most Cited Animal Genetics and Reproduction Papers, Class of 2026](https://pri.pepkio.com/top-papers/animal-genetics-and-reproduction/2026)

**Paper link:** [10.1097/tp.0000000000004958](https://doi.org/10.1097/tp.0000000000004958)

## Topics

pig-to-primate kidney xenotransplantation · hyperacute rejection · acute humoral xenograft rejection · preformed antipig natural antibodies · complement-dependent cytotoxicity · IgG-mediated rejection · IgM binding · GalTKO pig donors · human complement regulatory protein transgenic pigs · triple-KO multi-transgenic 10GE pigs · pig-to-baboon transplantation · pretransplant screening algorithms · antibody binding flow-cytometry assays · recipient screening thresholds · xenograft recipient selection

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Animal Genetics and Reproduction Papers, Class of 2026. https://pri.pepkio.com/top-papers/animal-genetics-and-reproduction/2026. Accessed 2026-07-22.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```