# Pharmacogenetic Approaches in Personalized Medicine for Postoperative Pain Management

*PRI Rank #14 · Topics and Trends in Most Cited Anesthesia and Pain Management Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/anesthesia-and-pain-management/2026/rank-14*

| Field | Value |
| --- | --- |
| Rank | #14 |
| 18m citations | 21 |
| Journal | Biomedicines |
| Year | 2024 |
| DOI | 10.3390/biomedicines12040729 |
| Corresponding authors | Daniel Humberto Pozza |
| Institution | University of Porto, Portugal |

**Ranking page:** [Topics and Trends in Most Cited Anesthesia and Pain Management Papers, Class of 2026](https://pri.pepkio.com/top-papers/anesthesia-and-pain-management/2026)

**Paper link:** [10.3390/biomedicines12040729](https://doi.org/10.3390/biomedicines12040729)

## Topics

Pharmacogenetics · Genotype-guided therapy · Postoperative pain management · opioid consumption · OPRM1 gene mutation · CYP2D6 polymorphism · CYP2C9 polymorphism · COMT gene variation · ABCB1 gene variation · analgesic efficacy · Perioperative care · Personalized medicine · Opioid prescribing · Drug metabolism enzymes

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Anesthesia and Pain Management Papers, Class of 2026. https://pri.pepkio.com/top-papers/anesthesia-and-pain-management/2026. Accessed 2026-07-14.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```