# Diagnostic performance of plasma pTau217, pTau181, Aβ1-42 and Aβ1-40 in the LUMIPULSE automated platform for the detection of Alzheimer disease

*PRI Rank #20 · Topics and Trends in Most Cited Alzheimer's disease research and treatments Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/alzheimer-s-disease-research-and-treatments/2026/rank-20*

| Field | Value |
| --- | --- |
| Rank | #20 |
| 18m citations | 94 |
| Journal | Alzheimer s Research & Therapy |
| Year | 2024 |
| DOI | 10.1186/s13195-024-01513-9 |
| Corresponding authors | Mireia Tondo, Daniel Alcolea |
| Institution | Hospital de La Santa Creu I Sant Pau, Spain |

**Ranking page:** [Topics and Trends in Most Cited Alzheimer's disease research and treatments Papers, Class of 2026](https://pri.pepkio.com/top-papers/alzheimer-s-disease-research-and-treatments/2026)

**Paper link:** [10.1186/s13195-024-01513-9](https://doi.org/10.1186/s13195-024-01513-9)

## Topics

p-tau217 · p-tau181 · Aβ42/40 ratio · LUMIPULSE platform · CSF Aβ42/40 ratio · Amyloid pathology detection · lumbar puncture · ROC analysis for diagnostic accuracy · plasma-CSF Spearman correlation · mild cognitive impairment · chronic kidney disease effect on biomarkers · two-cutpoint procedure · misclassification rate · Amyloid pathology detection · fold change in biomarker concentration · memory clinic cohort · blood-based Alzheimer biomarkers · cognitively unimpaired individuals · dementia classification · biomarker concordance with CSF amyloidosis

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Alzheimer's disease research and treatments Papers, Class of 2026. https://pri.pepkio.com/top-papers/alzheimer-s-disease-research-and-treatments/2026. Accessed 2026-07-24.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```