# Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes

*PRI Rank #14 · Topics and Trends in Most Cited Alzheimer's disease research and treatments Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/alzheimer-s-disease-research-and-treatments/2026/rank-14*

| Field | Value |
| --- | --- |
| Rank | #14 |
| 18m citations | 113 |
| Journal | Neuron |
| Year | 2024 |
| DOI | 10.1016/j.neuron.2024.06.029 |
| Corresponding authors | Michael T. Heneka |
| Institution | University Hospital Bonn, Germany |

**Ranking page:** [Topics and Trends in Most Cited Alzheimer's disease research and treatments Papers, Class of 2026](https://pri.pepkio.com/top-papers/alzheimer-s-disease-research-and-treatments/2026)

**Paper link:** [10.1016/j.neuron.2024.06.029](https://doi.org/10.1016/j.neuron.2024.06.029)

## Topics

Tunneling nanotubes (TNTs) · Microglia · α-synuclein aggregates · Tau accumulation · Mitochondrial transfer · Parkinson's disease · Alzheimer's disease · LRRK2 G2019S mutation · TREM2 T66M mutation · TREM2 R47H · oxidative stress · neuronal activity rescue · antimycin A · organelle transfer · neurodegenerative disease · microglia-neuron co-culture · neuroprotection · gene expression normalization · aggregate clearance · TNT formation

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Alzheimer's disease research and treatments Papers, Class of 2026. https://pri.pepkio.com/top-papers/alzheimer-s-disease-research-and-treatments/2026. Accessed 2026-07-24.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```