# Glutathione S-transferase: A versatile and dynamic enzyme

*PRI Rank #1 · Topics and Trends in Most Cited Agriculture and Biological Studies Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/agriculture-and-biological-studies/2026/rank-1*

| Field | Value |
| --- | --- |
| Rank | #1 |
| 18m citations | 48 |
| Journal | Biochemical and Biophysical Research Communications |
| Year | 2024 |
| DOI | 10.1016/j.bbrc.2024.150774 |
| Corresponding authors | Chinyere Aloke |
| Institution | University of the Witwatersrand, South Africa |

**Ranking page:** [Topics and Trends in Most Cited Agriculture and Biological Studies Papers, Class of 2026](https://pri.pepkio.com/top-papers/agriculture-and-biological-studies/2026)

**Paper link:** [10.1016/j.bbrc.2024.150774](https://doi.org/10.1016/j.bbrc.2024.150774)

## Topics

glutathione S-transferase · GST · enzyme versatility · enzyme dynamics · glutathione conjugation · Detoxification · xenobiotic metabolism · phase II metabolism · GST isoforms · catalytic mechanism · substrate specificity · protein structure-function · electrophilic substrates · glutathione binding · enzyme regulation

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Agriculture and Biological Studies Papers, Class of 2026. https://pri.pepkio.com/top-papers/agriculture-and-biological-studies/2026. Accessed 2026-10-29.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```