# A bioswitchable delivery system for microRNA therapeutics based on a tetrahedral DNA nanostructure

*PRI Rank #13 · Topics and Trends in Most Cited Advanced biosensing and bioanalysis techniques Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/advanced-biosensing-and-bioanalysis-techniques/2026/rank-13*

| Field | Value |
| --- | --- |
| Rank | #13 |
| 18m citations | 85 |
| Journal | Nature Protocols |
| Year | 2024 |
| DOI | 10.1038/s41596-024-01050-7 |
| Corresponding authors | Xiaoxiao Cai |
| Institution | Sichuan University, China |

**Ranking page:** [Topics and Trends in Most Cited Advanced biosensing and bioanalysis techniques Papers, Class of 2026](https://pri.pepkio.com/top-papers/advanced-biosensing-and-bioanalysis-techniques/2026)

**Paper link:** [10.1038/s41596-024-01050-7](https://doi.org/10.1038/s41596-024-01050-7)

## Topics

bioswitchable delivery system · microRNA therapeutics · Tetrahedral DNA nanostructure · DNA nanotechnology · Targeted drug delivery · stimuli-responsive nanocarrier · nucleic acid delivery · therapeutic RNA · DNA origami · controlled release · biocompatible nanostructure · gene therapy vector

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Advanced biosensing and bioanalysis techniques Papers, Class of 2026. https://pri.pepkio.com/top-papers/advanced-biosensing-and-bioanalysis-techniques/2026. Accessed 2026-07-22.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```