# Adipose tissue retains an epigenetic memory of obesity after weight loss

*PRI Rank #3 · Topics and Trends in Most Cited Adipose Tissue and Metabolism Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/adipose-tissue-and-metabolism/2026/rank-3*

| Field | Value |
| --- | --- |
| Rank | #3 |
| 18m citations | 201 |
| Journal | Nature |
| Year | 2024 |
| DOI | 10.1038/s41586-024-08165-7 |
| Corresponding authors | Ferdinand von Meyenn |
| Institution | ETH Zurich, Switzerland |

**Ranking page:** [Topics and Trends in Most Cited Adipose Tissue and Metabolism Papers, Class of 2026](https://pri.pepkio.com/top-papers/adipose-tissue-and-metabolism/2026)

**Paper link:** [10.1038/s41586-024-08165-7](https://doi.org/10.1038/s41586-024-08165-7)

## Topics

epigenetic memory · Adipose tissue · weight loss · Obesity · Single-nucleus RNA sequencing · Adipocyte · obesogenic memory · rebound weight gain · yo-yo effect · high-fat diet · Transcriptional profiling · epigenome alterations · metabolic stimuli response · epigenetic memory · weight maintenance · Adipocyte function · Mouse model · human adipose tissue

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Adipose Tissue and Metabolism Papers, Class of 2026. https://pri.pepkio.com/top-papers/adipose-tissue-and-metabolism/2026. Accessed 2026-07-22.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```