# Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity

*PRI Rank #1 · Topics and Trends in Most Cited Adipose Tissue and Metabolism Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/adipose-tissue-and-metabolism/2026/rank-1*

| Field | Value |
| --- | --- |
| Rank | #1 |
| 18m citations | 439 |
| Journal | New England Journal of Medicine |
| Year | 2024 |
| DOI | 10.1056/nejmoa2404881 |
| Corresponding authors | Atul Malhotra |
| Institution | University of California, San Diego, United States |

**Ranking page:** [Topics and Trends in Most Cited Adipose Tissue and Metabolism Papers, Class of 2026](https://pri.pepkio.com/top-papers/adipose-tissue-and-metabolism/2026)

**Paper link:** [10.1056/nejmoa2404881](https://doi.org/10.1056/nejmoa2404881)

## Topics

tirzepatide · obstructive sleep apnea · Obesity · apnea-hypopnea index · positive airway pressure · hypoxic burden · C-reactive protein · systolic blood pressure · sleep-related patient-reported outcomes · Body mass index · cardiovascular complications · Obesity · sleep-related patient-reported outcomes · gastrointestinal adverse events

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Adipose Tissue and Metabolism Papers, Class of 2026. https://pri.pepkio.com/top-papers/adipose-tissue-and-metabolism/2026. Accessed 2026-07-22.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```