# Comprehensive characterization of IFNγ signaling in acute myeloid leukemia reveals prognostic and therapeutic strategies

*PRI Rank #17 · Topics and Trends in Most Cited Acute Myeloid Leukemia Research Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/acute-myeloid-leukemia-research/2026/rank-17*

| Field | Value |
| --- | --- |
| Rank | #17 |
| 18m citations | 37 |
| Journal | Nature Communications |
| Year | 2024 |
| DOI | 10.1038/s41467-024-45916-6 |
| Corresponding authors | Hussein A. Abbas |
| Institution | The University of Texas MD Anderson Cancer Center, United States |

**Ranking page:** [Topics and Trends in Most Cited Acute Myeloid Leukemia Research Papers, Class of 2026](https://pri.pepkio.com/top-papers/acute-myeloid-leukemia-research/2026)

**Paper link:** [10.1038/s41467-024-45916-6](https://doi.org/10.1038/s41467-024-45916-6)

## Topics

IFNγ signaling · Acute myeloid leukemia (AML) · monocytic AML · T cells · NK cells · venetoclax resistance · bone marrow microenvironment · single-cell analysis · Immunosuppression · IFNγ signaling score · IFNγ signaling score · primary AML patient cells · immune evasion · IFNγ inhibition · prognostic biomarker · Bulk RNA sequencing · tumor surveillance

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Acute Myeloid Leukemia Research Papers, Class of 2026. https://pri.pepkio.com/top-papers/acute-myeloid-leukemia-research/2026. Accessed 2026-07-31.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```