# Molecular, clinical, and therapeutic determinants of outcome in <i>NPM1</i>-mutated AML

*PRI Rank #12 · Topics and Trends in Most Cited Acute Myeloid Leukemia Research Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/acute-myeloid-leukemia-research/2026/rank-12*

| Field | Value |
| --- | --- |
| Rank | #12 |
| 18m citations | 53 |
| Journal | Blood |
| Year | 2024 |
| DOI | 10.1182/blood.2024024310 |
| Corresponding authors | Richard Dillon |
| Institution | King's College London, United Kingdom |

**Ranking page:** [Topics and Trends in Most Cited Acute Myeloid Leukemia Research Papers, Class of 2026](https://pri.pepkio.com/top-papers/acute-myeloid-leukemia-research/2026)

**Paper link:** [10.1182/blood.2024024310](https://doi.org/10.1182/blood.2024024310)

## Topics

NPM1-mutated AML · FLT3-internal tandem duplication · Measurable residual disease (MRD) · DNMT3A · WT1 mutation · non-ABD NPM1 mutation · Adverse-risk cytogenetics · cumulative incidence of relapse · Overall survival · Allogeneic hematopoietic stem cell transplantation (allo-HSCT) · FLAG-Ida regimen · fludarabine · cytarabine · idarubicin · postinduction MRD status · Risk stratification · Intensive chemotherapy · molecular subgroups · First complete remission

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Acute Myeloid Leukemia Research Papers, Class of 2026. https://pri.pepkio.com/top-papers/acute-myeloid-leukemia-research/2026. Accessed 2026-07-31.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```